Caracterización microbiológica y molecular de la resistencia antimicrobiana de escherichia coli uropatógenas de hospitales públicos peruanos

Pool Marcos-Carbajal, Guillermo Salvatierra, José Yareta, Jimena Pino, Nancy Vásquez, Pilar Diaz, Isabel Martínez, Percy Asmat, Carlos Peralta, Caridad Huamani, Alexander Briones, Manuel Ruiz, Nicomedes Laura, Álvaro Luque, Leonel Arapa, Pablo Tsukayama

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

We characterized the antimicrobial resistance of 70 Escherichia coli isolates obtained from patients with a urinary tract infection (UTI) from 8 public hospitals in Peru. Resistance profiles were identified using the automated MicroScan® system. A standard polymerase chain reaction was used for the detection of the blaTEM, blaCTX-M, blaSHV and blaPER genes. The 65.7% (46/70) of the isolates presented a multidrug-re-sistant phenotype and 55.7% (39/70) were extended-spectrum beta-lactamases producers. High levels of resistance were detected for ampicillin (77,1%), ciprofloxacin (74,3%), trimethoprim/sulfamethoxazole (62,9%), cefepime (57,1%), and cefuroxime (57,1%). The blaTEM gene was the most frequent (31,4%), followed by blaCTX-M (18,6%) and blaSHV (2,9%) genes. These results show high resistance levels to antimi-crobials of clinical use in E. coli isolates from hospital UTI patients in Peru.

Translated title of the contributionMicrobiological and molecular characterization of antimicrobial resistance in uropathogenic escherichia coli from peruvian public hospitals
Original languageSpanish
Pages (from-to)119-123
Number of pages5
JournalRevista Peruana de Medicina Experimental y Salud Publica
Volume38
Issue number1
DOIs
StatePublished - 2021

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