PhTX-II a basic myotoxic phospholipase A₂ from Porthidium hyoprora snake venom, pharmacological characterization and amino acid sequence by mass spectrometry

Keyphrases

• Snake Venom 100%
• Phospholipase A2 (PLA2) 100%
• Mass Spectrometry 100%
• Pharmacological Characterization 100%
• Porthidium 100%
• Amino Acid Sequence 100%
• Myotoxic 100%
• Enzymatic Activity 42%
• Myotoxicity 28%
• Venom 28%
• Neuromuscular Blockade 28%
• Edema 14%
• CD Spectroscopy 14%
• Neuromuscular Preparations 14%
• Hydrophobic Channel 14%
• Ca2+ Binding 14%
• High Content 14%
• Catalytic Site 14%
• Catalytic Activity 14%
• Enzyme Class 14%
• α-helical Structure 14%
• Skeletal muscle Function 14%
• Toxic Actions 14%
• Secreted Phospholipase 14%
• High Catalytic Activity 14%
• Direct Action 14%
• Allosteric Behavior 14%
• Conserved Domain 14%
• Ca2+ 14%
• Tandem Mass Spectrometry 14%
• In Tandem 14%
• Autocatalytic Network 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Phospholipase A2 100%
• Snake Venom 100%
• Calcium Ion 100%
• Amino Acid 100%
• Edema 50%
• Phospholipase 50%
• Toxicity 50%
• Bird 50%

Biochemistry, Genetics and Molecular Biology

• Enzymatic Activity 66%