TY - JOUR
T1 - Point prevalence survey of antibiotic use in hospitals in Latin American countries
AU - Levy Hara, Gabriel
AU - Rojas-Cortes, Robin
AU - Molina León, Helvert Felipe
AU - Dreser Mansilla, Anahí
AU - Alfonso Orta, Ismary
AU - Rizo-Amezquita, Jose Noe
AU - Santos Herrera, Rene Guillermo
AU - Mendoza De Ayala, Silvia
AU - Arce Villalobos, Marlen
AU - Mantilla Ponte, Hilda
AU - Davila, Ever
AU - Aguilar, Gloria
AU - Porrás, Analiá
AU - Ramón-Pardo, Pilar
AU - Castro, Jose Luis
AU - Guzmán, Daniela
AU - Rioseco, Mariá Luisa
AU - Labarca, Jaime
AU - Madriz, Jose Pablo Diáz
AU - Cubero, Josue Murillo
AU - Calderón, Allan Robles
AU - Alfaro, Mónica
AU - Soto, Luisa Arias
AU - Aayon, Alejandro
AU - Oreamuno, Tania Jimenez
AU - Jimenez, Zulema
AU - Sequeira, Adriana
AU - Hernández, Jorge Mederos
AU - Lavaut, Jorge Luis Campistrous
AU - Meriño, Damarys Castillo
AU - Ruisanchez, Elsa Fleitas
AU - Sánchez, Damaris Portuondo
AU - Garcell, Humberto Guanche
AU - Socias, Juan Jose Pisonero
AU - Diáz, Evelyn Perera
AU - Lunar, Norma America Cardoso
AU - Lancis, Irene Fiterre
AU - Ramírez, Jose Antonio Álvarez
AU - Leyte, Midsay Lòpez
AU - Rosabal, Ariadna Mendez
AU - Estrada, Ebel Aldana
AU - Cano, Mariela
AU - Mendez, Leonel
AU - Eiriz, Anay Cordero
AU - Menendez, Liana Padrón
AU - Fernández, Gladys Fuentes
AU - Ayala, Raunel Reyes
AU - Monroy, Salomón
AU - Menjívar, Ramón
AU - Martínez, Carmen Elena Albanez
AU - Cabrera, Diana
AU - Delgado, Sofiá Mercedes Menjivar
AU - Guzmán, Gustavo Antonio Molina
AU - Mejiá, Rafael
AU - Rodríguez, Carolina
AU - Alvarenga, Sara
AU - Alvarado, Mirian
AU - De Zelaya, Ruth Del Carmen Alvarado
AU - Arevalo, Germán
AU - Parada, Guillermo
AU - Cuellar, Luis
AU - Ruiz, Alexis Holguín
AU - Pinedo, Yuan Almora
AU - Vergaray, Eduardo Sánchez
AU - Gil, Luis Enrique Vasquez
AU - Ibazeta, Bertha Gizel Injante
AU - Ricra, Esther Dina Guadalupe
AU - Segura, Rony Estrada
AU - Apac, Coralith Garciá
AU - Inga, Jennifer Cuadros
AU - Diáz, Roger Hernández
AU - Vigo, Marie Vallejo
AU - Cuba, Cesar Mujica
AU - Vilcapoma, Pierina
AU - Angles-Yanqui, Eddie
AU - Terrones, De Rocío Mananita
AU - Robles, Rosa Terán
AU - Resurrección, Cristhian
AU - Gonzalez, Alfredo Chiappe
AU - Antezana, Martha
AU - Zegarra, Socorro Torres
AU - Villegas-Chiroque, Miguel
AU - Diáz-Sipión, Roberto
AU - Benítez-Peche, Jorge
AU - Rosas, Jorge Luis Alave
AU - Ruiz, Jhoselyn Laura Goytizolo
AU - Fernández, Angelica Mariá Hernández
AU - Vargas, Jose Antonio Flores
AU - Araujo, Javier
AU - Garciá, Francisco Javier Arriaga
AU - Rivera, Zoila Cruz
AU - Colín, Víctor Monroy
AU - Ríos, Katia Bustamante
AU - Blanquel, Jorge Israel Hernández
AU - De La Garza, Eduardo Arias
AU - Gutierrez, Hector Hernández
AU - León, Karla
AU - Lara, Hortencia Esther Peralta
AU - Arias, Carlos Baltodano
AU - Garay, Eduardo Alemán
AU - Sanabria, Gladys Estigarribia
AU - Menchaca, Livio Mereles
AU - Vire, Natalia Luraschi
AU - Acuña, Dasy
AU - Caballero, Edgar Gimenez
N1 - Publisher Copyright:
© The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved.
PY - 2022/3/1
Y1 - 2022/3/1
N2 - Background: Point prevalence surveys (PPSs) on antibiotic use are useful for understanding different aspects related to prescription patterns in hospitals. Methods: An adaptation of the WHO methodology for a PPS on antibiotic use was applied. Hospital wards were divided into medical (MED), surgical (SUR), ICUs, gynaecology and obstetrics (GO), high-risk (HR) and mixed wards (MIX). A web application (RedCapVC ) through a mobile device was used for data collection. Results: Between December 2018 and August 2019, 5444 patients in 33 hospitals in five countries were included (10 hospitals in Cuba, 7 in Paraguay, 6 in El Salvador, 5 in Mexico and 5 in Peru). Of these patients, 54.6%received at least one antibiotic, with variations between and within hospitals and countries. Antibiotics were more frequently used in ICUs (67.2%), SUR (64.5%) and MED wards (54.2%), with 51.2% of antibiotics prescribed for community-acquired infections (CAIs), 22.9% for healthcare-associated infections (HAIs), 11.1% for surgical prophylaxis and 6.1% for unknown reasons. Adherence to guidelines was observed in 68.6% of cases (72.8% for CAIs, 72.4% for HAIs and 44.3% for prophylaxis). Third-generation cephalosporins were the class of antibiotics most frequently used (26.8%), followed by carbapenems (10.3%) and fluoroquinolones (8%). Targeted treatments were achieved in 17.3%of cases. Conclusions: Antibiotic use was generally higher than that published in other studies. There is an urgent need to promote and strengthen the antimicrobial stewardship programmes in Latin America.
AB - Background: Point prevalence surveys (PPSs) on antibiotic use are useful for understanding different aspects related to prescription patterns in hospitals. Methods: An adaptation of the WHO methodology for a PPS on antibiotic use was applied. Hospital wards were divided into medical (MED), surgical (SUR), ICUs, gynaecology and obstetrics (GO), high-risk (HR) and mixed wards (MIX). A web application (RedCapVC ) through a mobile device was used for data collection. Results: Between December 2018 and August 2019, 5444 patients in 33 hospitals in five countries were included (10 hospitals in Cuba, 7 in Paraguay, 6 in El Salvador, 5 in Mexico and 5 in Peru). Of these patients, 54.6%received at least one antibiotic, with variations between and within hospitals and countries. Antibiotics were more frequently used in ICUs (67.2%), SUR (64.5%) and MED wards (54.2%), with 51.2% of antibiotics prescribed for community-acquired infections (CAIs), 22.9% for healthcare-associated infections (HAIs), 11.1% for surgical prophylaxis and 6.1% for unknown reasons. Adherence to guidelines was observed in 68.6% of cases (72.8% for CAIs, 72.4% for HAIs and 44.3% for prophylaxis). Third-generation cephalosporins were the class of antibiotics most frequently used (26.8%), followed by carbapenems (10.3%) and fluoroquinolones (8%). Targeted treatments were achieved in 17.3%of cases. Conclusions: Antibiotic use was generally higher than that published in other studies. There is an urgent need to promote and strengthen the antimicrobial stewardship programmes in Latin America.
UR - http://www.scopus.com/inward/record.url?scp=85125212095&partnerID=8YFLogxK
U2 - 10.1093/jac/dkab459
DO - 10.1093/jac/dkab459
M3 - Article
C2 - 34957520
AN - SCOPUS:85125212095
SN - 0305-7453
VL - 77
SP - 807
EP - 815
JO - Journal of Antimicrobial Chemotherapy
JF - Journal of Antimicrobial Chemotherapy
IS - 3
ER -