TY - JOUR
T1 - Caracterización microbiológica y molecular de la resistencia antimicrobiana de escherichia coli uropatógenas de hospitales públicos peruanos
AU - Marcos-Carbajal, Pool
AU - Salvatierra, Guillermo
AU - Yareta, José
AU - Pino, Jimena
AU - Vásquez, Nancy
AU - Diaz, Pilar
AU - Martínez, Isabel
AU - Asmat, Percy
AU - Peralta, Carlos
AU - Huamani, Caridad
AU - Briones, Alexander
AU - Ruiz, Manuel
AU - Laura, Nicomedes
AU - Luque, Álvaro
AU - Arapa, Leonel
AU - Tsukayama, Pablo
N1 - Publisher Copyright:
© 2021, Instituto Nacional de Salud. All rights reserved.
PY - 2021
Y1 - 2021
N2 - We characterized the antimicrobial resistance of 70 Escherichia coli isolates obtained from patients with a urinary tract infection (UTI) from 8 public hospitals in Peru. Resistance profiles were identified using the automated MicroScan® system. A standard polymerase chain reaction was used for the detection of the blaTEM, blaCTX-M, blaSHV and blaPER genes. The 65.7% (46/70) of the isolates presented a multidrug-re-sistant phenotype and 55.7% (39/70) were extended-spectrum beta-lactamases producers. High levels of resistance were detected for ampicillin (77,1%), ciprofloxacin (74,3%), trimethoprim/sulfamethoxazole (62,9%), cefepime (57,1%), and cefuroxime (57,1%). The blaTEM gene was the most frequent (31,4%), followed by blaCTX-M (18,6%) and blaSHV (2,9%) genes. These results show high resistance levels to antimi-crobials of clinical use in E. coli isolates from hospital UTI patients in Peru.
AB - We characterized the antimicrobial resistance of 70 Escherichia coli isolates obtained from patients with a urinary tract infection (UTI) from 8 public hospitals in Peru. Resistance profiles were identified using the automated MicroScan® system. A standard polymerase chain reaction was used for the detection of the blaTEM, blaCTX-M, blaSHV and blaPER genes. The 65.7% (46/70) of the isolates presented a multidrug-re-sistant phenotype and 55.7% (39/70) were extended-spectrum beta-lactamases producers. High levels of resistance were detected for ampicillin (77,1%), ciprofloxacin (74,3%), trimethoprim/sulfamethoxazole (62,9%), cefepime (57,1%), and cefuroxime (57,1%). The blaTEM gene was the most frequent (31,4%), followed by blaCTX-M (18,6%) and blaSHV (2,9%) genes. These results show high resistance levels to antimi-crobials of clinical use in E. coli isolates from hospital UTI patients in Peru.
KW - Beta-Lactam Resistance
KW - Drug Resistance
KW - Escherichia coli
KW - Peru
KW - Urologic Diseases
UR - http://www.scopus.com/inward/record.url?scp=85111789116&partnerID=8YFLogxK
U2 - 10.17843/rpmesp.2021.381.6182
DO - 10.17843/rpmesp.2021.381.6182
M3 - Artículo
C2 - 34190903
AN - SCOPUS:85111789116
SN - 1726-4634
VL - 38
SP - 119
EP - 123
JO - Revista Peruana de Medicina Experimental y Salud Publica
JF - Revista Peruana de Medicina Experimental y Salud Publica
IS - 1
ER -