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Plataforma inteligente de trazabilidad para la certificación de la fibra de alpaca en microempresarios productores de la región Puno
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Financiamiento PE501091917-2024 - Plataforma trazabilidad fibra de alpaca
Plataforma digital inteligente y big data para el turismo rural comunitario en la región Puno
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EF-041 - Proyectos de investigación básica y aplicada
Programa Nacional de Investigación Científica y Estudios Avanzados
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Identification and quantification of components in extracts of Uncaria tomentosa by HPLC-ES/MS.
(2004)
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Carbone, V
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Quiroz, J de Dioz Zuniga
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De Simone, F
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Pizza, C
The two main classes of secondary metabolites, alkaloids and quinovic acid glycosides, of Uncaria tomentosa (Willd.) DC. (Rubiaceae), a Peruvian plant commonly known as 'uña de gato', have been analysed. Separation of the alkaloidal fraction was achieved using a solid phase extraction method based on cationic exchange, and an analytical method employing HPLC-ES/MS has been developed. Quantitative data for commercial wild bark, cultivated bark and leaves are reported. The analysis of quinovic acid glycosides was performed directly on the crude extract using both a fast analytical method based on flow injection ES/MS, and a more complete analytical technique using HPLC-MS.
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Status of the neuromyelitis optica spectrum disorder in Latin America
(2021-06-15)
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Fernando Hamuy
;
Verónica Rivas
;
Fernando Gracia
;
Juan Ignacio Rojas
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A case of monkeypox and cytomegalovirus coinfection manifesting with crusted lesions mimicking rupiod syphilis
(2023-11-03)
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Jhoann Aurich
;
José Quiroz
Human monkeypox is a viral zoonosis that has recently emerged worldwide. Clinical cutaneous features include papules, vesicles, and pustules. However, atypical manifestations mimicking other infectious diseases are being reported more frequently. We present a 41-year-old man patient with untreated HIV with generalized rupioid crusted ulcerated plaques with perineal ulceration that were found to represent monkeypox and cytomegalovirus infections.
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Simultaneous onset of acute myocardial infarction, bicuspid aortic stenosis, and cardiac transthyretin amyloidosis—A clinically complex confluence
(2024-01-01)
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Paol Rojas
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Roberto Baltodano‐Arellano
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Angela Cachicatari
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Jose A. Quiroz
The coexistence of bicuspid aortic valve disease and coronary artery disease is well-established, but the identification of cardiac amyloidosis in this population has surged with advancing imaging techniques, introducing complexities in patient management. This case report emphasizes the pivotal role of multimodality imaging in accurately diagnosing three concurrent pathologies.
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Novel Biomarkers for the diagnosis of diabetic nephropathy.
(2024-01-01)
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Juan Carlos Quiroz
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Jacsel Suárez
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José Enrique López Paz
;
Pela J Roseboom
Diabetes mellitus and its complications are a known public health problem nowadays. Diabetic nephropathy is one of the main complications and the result of multiple mechanisms, including: activation of the renin-angiotensin-aldosterone system, formation of advanced glycation end products and chronic inflammation that led to glomerular and tubulo-interstitial damage producing mesangial expansion and glomerulosclerosis, which finally results in chronic kidney disease. Early detection of diabetic nephropathy is essential for adequate intervention to stop, or at least slow down its progression. Multiple markers have been described, not only the classic ones such as serum creatinine, urea, and albuminuria, but at this point also novel biomarkers such as neutrophil gelatinase-associated lipocalin, tumor necrosis factor 1 receptor and monocyte chemoattractant protein-1, among others. The aim of this article was to provide an update review of the role of biomarkers in the diagnosis of diabetic nephropathy.

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