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Pancreatic secretion stimulated by a gastrin-like pentapeptide
Author(s)
Jorge E. Valenzuela
University of Chile
Margarita Petermann
University of Chile
University of Chile
Date Issued
1 de septiembre de 1968
Type
Article
Volume
13
Issue
9
Series/Report No.
Digestive Diseases and Sciences
Start Page
767
End Page
774
ISSN
0163-2116
1573-2568
Abstract
Duodenal content from subjects without pancreatic disease and 3 patients with chronic pancreatitis were studied after Pentagastrin (I.C.I. 50, 123) administration. The output of lipase and trypsin in patients with pancreatitis was lower than that in control subjects. Cholecystokinetic activity of Pentagastrin was evidenced by an increase of bilirubin content in duodenal aspirate. It is concluded that Pentagastrin may be used as a stimulant in pancreatic secretory studies.
Keywords