Point prevalence survey of antibiotic use in hospitals in Latin American countries
Author(s)
Gabriel Levy Hara
Robin Rojas-Cortés
Helvert Felipe Molina León
Anahí Dreser
Ismary Alfonso Orta
José Noe Rizo-Amezquita
René Guillermo Santos Herrera
Silvia Mendoza de Ayala
Marlen Arce Villalobos
Hilda Mantilla Ponte
Ever Davila
Gloria Aguilar
Analı́a Porrás
Pilar Ramón-Pardo
José L. Castro
on behalf of the Latin American Point Prevalent Survey Study Group
Daniela Guzmán
María Luisa Rioseco
Jaime Labarca
José Pablo Díaz Madriz
Josué Murillo Cubero
Allan Robles Calderón
Mónica Alfaro
Luisa Arias Soto
Alejandro Aayon
Tania Jiménez Oreamuno
Zulema Herrera Jiménez
Adriana Sequeira
Jorge Mederos Hernández
Jorge Luis Campistrous Lavaut
Damarys Castillo Meriño
Elsa Fleitas Ruisánchez
Damaris Portuondo Sánchez
Humberto Guanche Garcell
Juan José Pisonero Socías
Evelyn Perera Díaz
Norma America Cardoso Lunar
Irene Fiterre Lancís
José Antonio Ramírez
Midsay López Leyte
Ariadna Méndez Rosabal
Ebel Aldana Estrada
M. Bartolomé Cano
L. García Méndez
Anay Cordero Eiriz
Liana Padrón Menéndez
Gladys Fuentes Fernández
Raunel Reyes Ayala
Salomón Monroy
Ramón Menjívar
Carmen Elena Albanez Martínez
Diana Cabrera
Sofía Mercedes Menjivar Delgado
Gustavo Guzman
Rafael Jiménez-Mejía
Carolina Rodríguez
Sara Alvarenga
Mirian Alvarado
Ruth del Carmen Alvarado de Zelaya
Germán Arévalo
Guillermo Parada
Luis Cuéllar
Alexis Holguín Ruiz
Yuan Almora Pinedo
Eduardo Sánchez Vergaray
Luis Enrique Vasquez Gil
Bertha Gizel Injante Ibazeta
Esther Dina Guadalupe Ricra
Rony Estrada Segura
Coralith García Apac
Jennifer Cuadros Inga
Roger Hernández Díaz
Marie Vallejo Vigo
Cesar Mujica Cuba
Pierina Vilcapoma
Eddie Angles-Yanqui
Débora Rocío Mananita Terrones
Rosa Terán Robles
Cristhian Resurrección
Alfredo Chiappe-Gonzalez
Martha Antezana
Socorro Torres Zegarra
Miguel Villegas-Chiroque
Roberto Díaz-Sipión
Jorge Marko A. Benitez-Peche
Jhoselyn Laura Goytizolo Ruiz
Angélica María Hernández Fernández
José Antonio Flores Vargas
Javier Araujo
Francisco Javier Arriaga García
Zoila Cruz Rivera
Víctor Monroy Colín
Katia Bustamante Ríos
Jorge Israel Hernández Blanquel
Eduardo Arias de la Garza
Héctor Hernández Gutiérrez
Karla Johanna Banegas León
Hortencia Esther Peralta Lara
Carlos Baltodano Arias
Eduardo Alemán Garay
Gladys Estigarribia
Livio Mereles Menchaca
Natalia Luraschi Viré
Dasy Acuña
Edgar Giménez Caballero
Date Issued
1 de diciembre de 2021
Type
Article
Volume
77
Issue
3
Start Page
807
End Page
815
Abstract
BACKGROUND: Point prevalence surveys (PPSs) on antibiotic use are useful for understanding different aspects related to prescription patterns in hospitals. METHODS: An adaptation of the WHO methodology for a PPS on antibiotic use was applied. Hospital wards were divided into medical (MED), surgical (SUR), ICUs, gynaecology and obstetrics (GO), high-risk (HR) and mixed wards (MIX). A web application (RedCap©) through a mobile device was used for data collection. RESULTS: Between December 2018 and August 2019, 5444 patients in 33 hospitals in five countries were included (10 hospitals in Cuba, 7 in Paraguay, 6 in El Salvador, 5 in Mexico and 5 in Peru). Of these patients, 54.6% received at least one antibiotic, with variations between and within hospitals and countries. Antibiotics were more frequently used in ICUs (67.2%), SUR (64.5%) and MED wards (54.2%), with 51.2% of antibiotics prescribed for community-acquired infections (CAIs), 22.9% for healthcare-associated infections (HAIs), 11.1% for surgical prophylaxis and 6.1% for unknown reasons. Adherence to guidelines was observed in 68.6% of cases (72.8% for CAIs, 72.4% for HAIs and 44.3% for prophylaxis). Third-generation cephalosporins were the class of antibiotics most frequently used (26.8%), followed by carbapenems (10.3%) and fluoroquinolones (8%). Targeted treatments were achieved in 17.3% of cases. CONCLUSIONS: Antibiotic use was generally higher than that published in other studies. There is an urgent need to promote and strengthen the antimicrobial stewardship programmes in Latin America.
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