Cargando...
Detección de virus influenza A, B y subtipos A (H1N1) pdm09, A (H3N2) por múltiple RT-PCR en muestras clínicas
Author(s)
Instituto Nacional de Salud
Maribel Huaringa
Instituto Nacional de Salud
Nancy Rojas
Instituto Nacional de Salud
Victoria Gutiérrez
Instituto Nacional de Salud
Sila Ruiton
Instituto Nacional de Salud
Emelda Gallardo
Instituto Nacional de Salud
Jorge Achata
Instituto Nacional de Salud
Marco Galarza
Instituto Nacional de Salud
Date Issued
30 de junio de 2017
Type
Article
Volume
34
Issue
2
Series/Report No.
Revista Peruana de Medicina Experimental y Salud Pública
Start Page
192
End Page
192
ISSN
1726-4634
1726-4642
Abstract
OBJECTIVES.: To describe the clinical and epidemiological characteristics of patients diagnosed with epidermolysis bullosa (EB) at the Instituto Nacional de Salud (INSN) in Lima, Peru; a National Reference Center for this disease. MATERIAL AND METHODS: . Observational, descriptive and transversal study. We reviewed the clinical histories and laboratory tests of patients diagnosed with EB treated in INSN from 1993 to 2015. RESULTS.: 93 patients were registered. The average age was 7.9 ± 5.6 years; 53.8% (n = 50) were boys. Clinical forms corresponded to dystrophic EB with 41 (44.1%) cases, simple EB with 39 (41.9%) union EB cases with 8 (8.6%) and Kindler syndrome with 4 (4.3%) cases. The clinical form could not be identified in a case. A total of 48 cases (51.6%) came from Lima and Callao, and 45 cases (48.4%) from other provinces of the country. Extracutaneous manifestations involved gastrointestinal (44.1%), ocular (37.6%), odontogenic (87.1%), and nutritional (79.6%) involvement, as well as pseudosindactilia (16.1%). Chronic malnutrition (71.6%), acute malnutrition (17.6%) and anemia (62.4%) were found. Mortality corresponded to 6 cases (6.5%). CONCLUSIONS.: 93 cases of EB were reported in INSN, the predominant clinical presentation was the dystrophic form.
Keywords