Case Report: Neurobrucellosis Presenting as Malignancy

Salcedo, Andrea S.; Carreras, Xosse; Kobayashi, Takaaki; Salinas, Jorge L.; Muñoz, Sara; Diaz Reyes, Nelson Fidel; Alave Rosas, Jorge Luis

doi:10.4269/ajtmh.23-0684

Case Report: Neurobrucellosis Presenting as Malignancy

Author(s)

Salcedo, Andrea S.

Peruvian University of Applied Sciences

Carreras, Xosse

Peruvian University of Applied Sciences

Kobayashi, Takaaki

University of Iowa Hospitals and Clinics

Salinas, Jorge L.

Stanford University

Muñoz, Sara

Diaz Reyes, Nelson Fidel

Universidad Peruana Unión

Alave Rosas, Jorge Luis

Universidad Peruana Unión

Date Issued

11 de junio de 2024

Type

Article

Volume

111

Issue

2

Series/Report No.

American Journal of Tropical Medicine and Hygiene

Start Page

312

End Page

316

DOI

10.4269/ajtmh.23-0684

ISSN

0002-9637

1476-1645

Abstract

Neurobrucellosis, caused by Brucella species, is a zoonotic infection that may involve the central nervous system. Although uncommon, it can manifest as a solitary intracranial mass. We report a case of neurobrucellosis in a 25-year-old woman from Peru who presented with headache, weight loss, and right-side hemiparesis and paresthesia. A contrast-enhanced magnetic resonance imaging scan revealed an intracerebral mass in the left temporal lobe. Serum testing subsequently were positive. Brain biopsy demonstrated non-necrotizing granulomas without malignant cells. Neurobrucellosis should be considered in the differential diagnosis of brain space occupying lesions in endemic countries.