Alvarez Manrique, Victor Daniel

Cargando...
Miniatura
Nombre preferido
Alvarez Manrique, Victor Daniel
Afiliación principal
Correo electrónico
victor.alvarez@upeu.edu.pe
ORCID
ID de autor de Scopus

Ajustes

Mostrando 1 - 10 de 24
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Novel mutations associated with nephrogenic diabetes insipidus. A clinical-genetic study
    (2015-04-21)
    RenalTube Group  
    ;
    Alejandro García‐Castaño
    ;
    Gustavo Pérez de Nanclares
    ;
    Leire Madariaga
    ;
    Mireia Aguirre
    Citas (OpenAlex): 29
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Validation of a Job Satisfaction Scale among Health Workers
    (2024-03-10)
    Allison Ramirez-Cruz
    ;
    Caleb Sucapuca
    ;
    Mardel Morales-García  
    ;
    Víctor Álvarez-Manrique  
    ;
    Liset Z. Sairitupa-Sanchez
    Background: job satisfaction is a key focus in organizational behavior studies, particularly relevant in the healthcare sector and nursing. It influences patient care quality and staff retention and is shaped by the work environment, working conditions, managerial support, and interactions among colleagues. However, there is limited research specifically addressing the job satisfaction of nurses in Peru, a critical area in health administration. Objective: this study aimed to evaluate the metric properties of the S20/23 job satisfaction scale among Peruvian nurses. Methods: an instrumental research design was employed using a non-probabilistic sample of 325 nurses from two hospitals in Lima, Peru. The Chilean version of the S20/23 scale was used, comprising four dimensions of job satisfaction (relationship with supervision, physical work space, professional fulfillment, and training and decision-making opportunities). Data analysis included descriptive statistics, confirmatory factor analysis (CFA), and reliability tests using Cronbach's Alpha and McDonald's Omega. Results: the CFA revealed a satisfactory fit for the four-dimensional structure with 18 items (χ2 = 387,290, df = 124, p < ,001, CFI = 0,92, TLI = 0,90, RMSEA = 0,08, SRMR = 0,05). The scale also demonstrated high reliability for each dimension: relationship with supervision (α = 0,90, ꞷ = 0,87), physical work space (α, ꞷ = 0,92), professional fulfillment (α, ꞷ = 0,88), and training and decision-making opportunities (α = 0,88, ꞷ = 0,84), with acceptable factor loadings (>0,70). Conclusions: the adapted 18-item S20/23 scale is a valid and reliable tool for assessing job satisfaction among Peruvian nurses. The study highlights the importance of specific job satisfaction dimensions, such as relationships with supervisors and professional development opportunities, in the Peruvian nursing context
    Citas (OpenAlex): 1
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Establishing an online resource to facilitate global collaboration and inclusion of underrepresented populations: Experience from the MJFF Global Genetic Parkinson’s Disease Project
    (2023-10-03)
    Eva‐Juliane Vollstedt  
    ;
    Harutyun Madoev
    ;
    Anna Aasly
    ;
    Azlina Ahmad‐Annuar
    ;
    Bashayer Al‐Mubarak
    Parkinson's disease (PD) is the fastest-growing neurodegenerative disorder, currently affecting ~7 million people worldwide. PD is clinically and genetically heterogeneous, with at least 10% of all cases explained by a monogenic cause or strong genetic risk factor. However, the vast majority of our present data on monogenic PD is based on the investigation of patients of European White ancestry, leaving a large knowledge gap on monogenic PD in underrepresented populations. Gene-targeted therapies are being developed at a fast pace and have started entering clinical trials. In light of these developments, building a global network of centers working on monogenic PD, fostering collaborative research, and establishing a clinical trial-ready cohort is imperative. Based on a systematic review of the English literature on monogenic PD and a successful team science approach, we have built up a network of 59 sites worldwide and have collected information on the availability of data, biomaterials, and facilities. To enable access to this resource and to foster collaboration across centers, as well as between academia and industry, we have developed an interactive map and online tool allowing for a quick overview of available resources, along with an option to filter for specific items of interest. This initiative is currently being merged with the Global Parkinson's Genetics Program (GP2), which will attract additional centers with a focus on underrepresented sites. This growing resource and tool will facilitate collaborative research and impact the development and testing of new therapies for monogenic and potentially for idiopathic PD patients.
    Citas (OpenAlex): 7metric-badges.view 1
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Ureterocele urothelial carcinoma: managing a rare presentation
    (2016-02-16)
    Juan Astigueta  
    ;
    Milagros Abad‐Licham
    ;
    Eloy Silva
    ;
    Victor E. Alvarez
    ;
    Francis Piccone
    It is very uncommon for urothelial carcinoma to develop in an ureterocele. It is generally discovered in an imaging study or in connection with haematuria. We found very few reports in the literature. Here, we report on the case of a 71-year-old male who initially presented with haematuria and low back pain and who then underwent transurethral resection for an intraureterocele tumour. Pathology confirmed urothelial carcinoma.
    Citas (OpenAlex): 6
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Maternal microbiota: changes and consequences during pregnancy. a narrative review
    (2025-02-18)
    Melany Tello-Silva
    ;
    Mardel Morales-García  
    ;
    Liset Z. Sairitupa-Sanchez
    ;
    Víctor Álvarez-Manrique  
    ;
    Víctor Álvarez-Manrique  
    Objective:This study aims to review the changes in microbiota during pregnancy, characterized by natural and associative aspects. Design: A literature review based on a narrative synthesis. Data Sources: The study was conducted using databases such as PubMed, Science Direct, Web of Science (WOS), Scielo, and Google Scholar. Study Selection: Documents were selected and analyzed through an exhaustive literature review, applying specific inclusion and exclusion criteria. Results: For the results analysis, 15 articles were selected, including 3 observational studies, 4 clinical trials, 7 statistical analyses, 2 systematic reviews, and 1 narrative review. The research population consisted of both healthy pregnant women and those with pre-existing conditions. Some studies were conducted in Europe, the United States, Australia, China, and South America. Conclusion: Changes in microbiota during pregnancy influence body mass index (BMI) and are associated with hypertensive disorders, gestational diabetes, the use of prebiotic supplements, and periodontitis. Moreover, microbiota is naturally linked to vaginal function changes, contributes to the infant’s immune system development, and provides beneficial bacteria through breast milk.
    Citas (OpenAlex): 0metric-badges.view 1
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Covid-19 with gastrointestinal symptoms: a narrative review
    (2025-02-18)
    Janeth Vásquez-Granda
    ;
    Jessy C. Tarrillo-Olivos
    ;
    Naomy R. Pereyra-Urbina
    ;
    Jhanina Paola Jhanina Paola
    ;
    Yajahira M. Cabanillas-Carrero
    Objective: This study aims to conduct a brief literature review on gastrointestinal problems caused by COVID-19, characterized by symptoms and sequelae.Design: Literature review based on a narrative synthesis.Data sources: Databases: Scopus, Web of Science, Science Direct, Scielo, Google Scholar.Study selection: The documents were selected and analyzed under a critical literature review, considering inclusion and exclusion criteria.Results: Out of a total of 461,161 potentially relevant articles, the analysis was based on 19 studies, of which 10 were statistical analyses, 5 were narrative reviews, and 3 were systematic reviews. Patients involved in these studies not only exhibited gastrointestinal conditions due to COVID-19 but also experienced neurological, cardiovascular issues, and pneumonia. The study populations included children, young adults, adults, and pregnant women, with studies conducted in the United States, China, Morocco, Iran, Mexico, Colombia, and Brazil.Conclusions: COVID-19 has caused gastrointestinal problems such as diarrhea, abdominal pain, vomiting, and persistent sequelae like irritable bowel syndrome (IBS), erectile dysfunction, and functional dyspepsia. Adults also face psychosocial disorders, such as anxiety and depression. Long-term sequelae include cognitive disorders, fatigue, hypertension, and chronic respiratory problems. Severe patients are at higher risk for coagulopathies and require intensive care. These sequelae significantly impact quality of life, increase psychological stress, and contribute to economic burdens.
    Citas (OpenAlex): 0metric-badges.view 1
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Crohn’s disease: a narrative review
    (2026-01-01)
    Wilter C. Morales García
    ;
    Víctor Álvarez-Manrique  
    ;
    Mardel Morales-García  
    ;
    Piero Alexander Vargas Ruiz
    ;
    Bilha Raquel Pisco Salas
    Objective: to conduct a literature review of Crohn's disease based on its causes, risks, and treatments.Method: a literature review based on narrative and systematic synthesis.
    Citas (OpenAlex): 0metric-badges.view 1
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Repurposed Antiviral Drugs for Covid-19 — Interim WHO Solidarity Trial Results
    (2020-12-02)
    WHO Solidarity Trial Consortium  
    BACKGROUND: World Health Organization expert groups recommended mortality trials of four repurposed antiviral drugs - remdesivir, hydroxychloroquine, lopinavir, and interferon beta-1a - in patients hospitalized with coronavirus disease 2019 (Covid-19). METHODS: We randomly assigned inpatients with Covid-19 equally between one of the trial drug regimens that was locally available and open control (up to five options, four active and the local standard of care). The intention-to-treat primary analyses examined in-hospital mortality in the four pairwise comparisons of each trial drug and its control (drug available but patient assigned to the same care without that drug). Rate ratios for death were calculated with stratification according to age and status regarding mechanical ventilation at trial entry. RESULTS: At 405 hospitals in 30 countries, 11,330 adults underwent randomization; 2750 were assigned to receive remdesivir, 954 to hydroxychloroquine, 1411 to lopinavir (without interferon), 2063 to interferon (including 651 to interferon plus lopinavir), and 4088 to no trial drug. Adherence was 94 to 96% midway through treatment, with 2 to 6% crossover. In total, 1253 deaths were reported (median day of death, day 8; interquartile range, 4 to 14). The Kaplan-Meier 28-day mortality was 11.8% (39.0% if the patient was already receiving ventilation at randomization and 9.5% otherwise). Death occurred in 301 of 2743 patients receiving remdesivir and in 303 of 2708 receiving its control (rate ratio, 0.95; 95% confidence interval [CI], 0.81 to 1.11; P = 0.50), in 104 of 947 patients receiving hydroxychloroquine and in 84 of 906 receiving its control (rate ratio, 1.19; 95% CI, 0.89 to 1.59; P = 0.23), in 148 of 1399 patients receiving lopinavir and in 146 of 1372 receiving its control (rate ratio, 1.00; 95% CI, 0.79 to 1.25; P = 0.97), and in 243 of 2050 patients receiving interferon and in 216 of 2050 receiving its control (rate ratio, 1.16; 95% CI, 0.96 to 1.39; P = 0.11). No drug definitely reduced mortality, overall or in any subgroup, or reduced initiation of ventilation or hospitalization duration. CONCLUSIONS: These remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19, as indicated by overall mortality, initiation of ventilation, and duration of hospital stay. (Funded by the World Health Organization; ISRCTN Registry number, ISRCTN83971151; ClinicalTrials.gov number, NCT04315948.).
    Citas (OpenAlex): 2620metric-badges.view 5
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Mpox: Transmission, clinical manifestations, prevention, and treatment – a narrative review
    (2025-02-18)
    Erica Sandoval-Urbano
    ;
    Jhonny E. Pimentel-Betancourt
    ;
    Kelita M. Lozano-Gutierres
    ;
    Mirian Julca-Cano
    ;
    Víctor Álvarez-Manrique  
    Objective:To identify the transmission methods, symptoms, complications, prevention, and treatment associated with Mpox. Design:Literature review based on a narrative synthesis. Data Sources:Web of Science, Google Scholar, Scielo, ScienceDirect, Redalyc, and Scopus. Study Selection:Documents were selected and analyzed through a critical literature review, considering inclusion and exclusion criteria. Results:A literature review was conducted with a corpus of 17 articles, including 11 narrative reviews, 2 systematic reviews, and 4 statistical analyses. Mpox is more prevalent among children, adults, pregnant women, and homosexual and bisexual individuals. The regions with the highest outbreak incidence are Asia, South America, Europe, the United States, and especially West and Central Africa, where it is endemic. Clinical conditions associated with Mpox include fever, skin rashes, abdominal pain, and meningitis, and it is strongly linked to HIV. Most reported cases have been among lower-class individuals, with some from the middle class. Conclusions: The Mpox virus is transmitted through various means, primarily contact, bodily fluids, and sexual relations between men. It significantly affects children and pregnant women and presents a range of symptoms, with skin lesions being the most frequent, followed by fever, headaches, oral lesions, and others. If left untreated or inadequately managed, it can lead to severe complications, with HIV-positive individuals and immunocompromised patients at the highest risk. Pneumonia can be fatal in severe cases. Good personal hygiene is recommended, and although there are no approved vaccines for Mpox, Tecovirimat and Brincidofovir show potential for approval in case of future outbreaks.
    Citas (OpenAlex): 1
  • Publicacion
    Algunas métricas están bloqueadas por su 
    configuración de consentimiento
    Item type:Publicación,
    Associated and clinical factors in patients with diabetes: a narrative review
    (2026-01-01)
    Abigail Flores Tocto
    ;
    Vanessa Arce Onorbe
    ;
    Flor Muñoz Villalobos
    ;
    Wilter C. Morales García
    ;
    Víctor Álvarez-Manrique  
    Objective: to identify associated factors and clinical factors in patients with diabetes.Method: Literature review based on a narrative synthesis.Data sources: Scopus, Google Scholar, Pubmed.Data selection: Documents were selected and analyzed based on a critical literature review, taking into account the inclusion and exclusion criteria.Results: a corpus of 13 articles was analyzed: cross-sectional, retrospective, randomized controlled trial, Mendelian randomization, prospective observational, cohort study, qualitative study, analytical study, and observational cohort study.The population studied in the articles included various categories: adults, women, and minors.The studies were conducted in various countries: China, the United Kingdom, Spain, Norway, Iran, Turkey, Saudi Arabia, and India.Associated factors were self-care, depression, insulin use, obesity, and elevated plasma glucose.Clinical factors were identified as nephropathy, heart failure, postoperative diabetes insipidus, and glycemic control.Regarding socioeconomic status, the studies were conducted in lowincome, high-income, and middle-income countries.Conclusion: diabetes mellitus is a public health problem influenced by associated factors such as lifestyle and social environment, and clinical factors such as hyperglycemia and hypertension.Early diagnosis and self-care are essential to prevent complications.
    Citas (OpenAlex): 0metric-badges.view 1