Effects of HPV 16 in women with cervical cancer: A narrative review

Objective: to identify associated factors and clinical factors in patients with diabetes.Method: literature review based on a narrative synthesis.Data sources: Scopus, Science direct, Web of sciencie, Google scholar, PubMed and SciELO.Data selection: The documents were selected and analyzed under a critical review of the literature taking into account the inclusion and exclusion criteria.Results: a corpus of 17 articles was analyzed, of which 7 performed quantitative analyses, 2 retrospective cohort studies, 3 observational studies, 1 experimental methodology study, 1 cross-sectional study, 1 systematic review and 2 descriptive studies.The population studied in the articles includes various categories: women between 30 and 65 years old, adolescents and adults over 60 years old, women attending gynecological check-ups, indigenous women from rural and urban areas and women with prevalence of cervical cancer and other types of carcinomas, in addition to studies for the development of prophylactic vaccines.The studies were carried out in various countries: 2 Turkey, 1 Spain, 1 Chile, 3 Ecuador, 3 China, 1 Indonesia, 1 Mexico, 1 Argentina, 2 Colombia, 1 Italy, each providing a unique perspective to the research.Negative cytology was analyzed in three articles highlighting its presence in healthy women carrying the Human Papillomavirus.Seven articles were also identified that address the prevalence and types of HPV, two that point to factors associated with the development of cervical cancer, and six that address high-and low-grade lesions.Regarding socioeconomic status, 12 articles were conducted in populations in low-income countries, only three were from high-income countries, and one was from a middle-income country.Conclusion: the review showed that HPV type 16 is strongly associated with cervical cancer, with significant impacts in diverse populations and socioeconomic contexts.The studies highlight severe symptoms and high mortality, highlighting the need to strengthen prevention and treatment, especially in resource-limited countries.